Should all incidentally discovered adrenal masses be resected?
No. Incidentally discovered, clinically occult adrenal masses, referred to as incidentalomas, are common (4.4% in modern abdominal computed tomography [CT] series) and increasingly encountered with the ubiquity of abdominal CT. Most incidentally discovered adrenal nodules are nonfunctional and benign (80% are cortical adenomas), requiring only surveillance. Adrenalectomy is indicated for tumors > 4 cm, imaging characteristics concerning for malignancy, and biochemically hyperactive lesions.