Role of subcellular compartments of the canonical neuron in disease

Role of subcellular compartments of the canonical neuron in disease

How are the major subcellular compartments of the canonical neuron affected in disease?

Soma

site of pathological inclusions in neurodegenerative diseases

Dendrites

loss of dendritic spines in autism

Axon

susceptibility to shearing in traumatic brain injury, loss in Wallerian degeneration

Nodes of Ranvier

susceptibility to dysfunction in channelopathies

Myelin

loss in demyelinating diseases

15585

Sign up to receive the trending updates and tons of Health Tips

Join SeekhealthZ and never miss the latest health information

15856