Role of kidney transplantation in nephrotic syndrome

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What is the role of kidney transplantation in the treatment of patients with nephrotic syndrome?

Kidney transplantation is a viable option in all patients with nephrotic syndrome who progress to ESKD.

However, there is a substantial risk of recurrent disease that is in the range of 20% to 40% for patients with FSGS and MPGN.

Thus, patients who have lost more than one kidney allograft to recurrent glomerular disease are often considered ineligible for subsequent transplant procedures.

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