Role of IV iron

What is the role of IV iron?

Studies have demonstrated that functional iron deficiency is common in patients with end-stage kidney disease (ESKD) who are treated with ESAs and that IV iron supplementation decreases ESA requirements by 20% to 25%.

In Chronic kidney disease patients with iron deficiency anemia not receiving ESAs, 1 gm IV iron generally raises the Hb 1 gm/dL. For iron-deficient, non-hemodialysis patients who fail oral iron therapy, IV iron can be given in larger doses over fewer treatments for patient convenience and vein sparing. In HD patients, IV iron is generally administered in smaller, more frequent doses through the dialysis circuit.

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