Possible causes of fever and polyarthritis

Possible causes of fever and polyarthritis

Infectious arthritis: septic arthritis, bacterial endocarditis, Lyme disease, viral arthritis

Reactive arthritis: enteric infections, genitourinary infections

Systemic rheumatic diseases: RA∗, SLE∗, Still’s disease, systemic vasculitis

Crystal-induced arthritis: gout, pseudogout

Miscellaneous disease: malignancy, familial Mediterranean fever, rheumatic fever, dermatomyositis, sarcoidosis, Behcet’s disease, inflammatory bowel disease, Henoch–Schönlein purpura, Kawasaki’s disease, erythema nodosum, erythema multiforme, Whipple’s disease, relapsing polychondritis

∗Note that fever as a disease manifestation of RA and SLE is uncommon. In such patients, especially in the presence of immunosuppressive medications, a fever should be presumed secondary to infection until proven otherwise.


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