Phases of Takayasu Arteritis

Phases of Takayasu Arteritis

How does Tak ayasu Arteritis present?

A triphasic pattern of progression of disease is classically described:

• Phase I: pre-pulseless, ‘inflammatory’ period characterized by systemic complaints, such as fever, arthralgias, and weight loss, often misdiagnosed as an infectious syndrome.

• Phase II: vessel inflammation, dominated by vessel pain and tenderness.

• Phase III: fibrotic stage, when bruits and ischemia predominate.

Patients can present in any phase or combination of phases because TA is a chronic, recurrent disease.

Up to 10% present with no symptoms, and the incidental finding of unequal pulses/BPs, bruits, or hypertension prompts further evaluation.


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