Neurologic manifestations of celiac disease

What are the neurologic manifestations of celiac disease? 

Celiac disease, or gluten enteropathy, is an autoimmune disease of the small intestine that produces chronic small bowel malabsorption of vitamins and other nutrients often with iron deficiency anemia, osteoporosis and osteomalacia, and hypoalbuminemia. Individuals with the disease are intolerant to gluten proteins that are present in rye, wheat, barley, and in some adhesives, including that of stamps and envelopes.

Ten percent of affected patients have neurologic complaints, the most notable being cerebellar dysfunction secondary to chronic fat malabsorption.

Tremor, intranuclear ophthalmoplegia, encephalopathy, subacute combined degeneration, seizures, or myopathy are other features associated with the disease.

The observed myopathy is often treatable by vitamin D replacement. 

Sources

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