Mechanism of action of somatostatin analogues
- Most GH-secreting tumors have somatostatin receptors and respond to exogenous somatostatin with decreases in GH levels.
- The development of long-acting somatostatin analogues (octreotide long-acting release, lanreotide autogel/depot, and pasireotide) was a major advance in the treatment of acromegaly.
