Mechanism of action of somatostatin analogues

Mechanism of action of somatostatin analogues

Most GH-secreting tumors have somatostatin receptors and respond to exogenous somatostatin with decreases in GH levels. The development of long-acting somatostatin analogues (octreotide long-acting release, lanreotide autogel/depot, and pasireotide) was a major advance in the treatment of acromegaly.

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