Mechanism of action of mirtazapine

What is the mechanism of action of mirtazapine and how might the side effects of this medication be used therapeutically? 

Mirtazapine is an antidepressant that acts as an inhibitor of presynaptic alpha-2-noradrenergic receptors and causes an increase in release of serotonin and norepinephrine.

It also blocks serotonin (5-HT2, 5-HT3), and histamine (H1) and as a result can improve nausea, stimulate appetite, and treat insomnia.


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