Major contraindications to the administration of intravascular contrast material

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What are the major contraindications to the administration of intravascular contrast material?

• Patient refuses to receive intravascular contrast material.

• Patient did not receive premedication, when indicated, prior to scheduled contrast administration.

• Patient has renal insufficiency.

• Patient has thyroid disease that will be treated with systemic 131 I radiotherapy. This contraindication applies for iodinated, not gadolinium-based, contrast material only. The reason is that iodinated contrast material transiently decreases 131 I radiotracer uptake in the thyroid gland, potentially decreasing the effectiveness of subsequent radioiodide therapy.

• Patient is pregnant. This contraindication particularly applies for the intravascular administration of gadolinium-based contrast material.

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