When is premedication indicated prior to contrast administration

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When is premedication indicated prior to contrast administration?

The primary indication for premedication prior to contrast-enhanced imaging is the pretreatment of patients at increased risk for an acute allergic-like reaction to contrast material. Premedication generally involves the administration of corticosteroids, sometimes in conjunction with H1 blockers.

At our institution, indications for premedication include:

  • • Prior moderate or severe allergic-like reaction to contrast material.
  • • Prior intravenous contrast reaction requiring administration of epinephrine.
  • • Prior life-threatening reaction to any allergen or medication.
  • • Presence of asthma with active wheezing.
  • • Presence of asthma requiring intubation in the last 3 months.

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