What is the mainstay of treatment for patients with TTP?
Prompt initiation of plasmapheresis with fresh frozen plasma is the most important treatment for TTP. In acquired TTP, plasmapheresis has the benefit of removing the autoantibodies in the patient’s blood.
In hereditary TTP, plasma infusion as opposed to plasmapheresis is indicated. Glucocorticoids may be of benefit in patients with acquired TTP (decrease the production of autoantibodies to ADAMTS13).
