Latest Treatment options for hyperaldosteronism

Latest Treatment options for hyperaldosteronism

• Conn adenoma: Unilateral adrenalectomy, now often by laparoscopic surgery.

• Bilateral adrenal hyperplasia: Chronic therapy with an aldosterone antagonist. Spironolactone had superior efficacy in lowering blood pressure compared to eplerenone in one international clinical trial, but the latter has fewer adverse effects.

• For hyperaldosteronism related to sleep apnea: Spironolactone (or eplerenone) is effective in the vast majority of cases; continuous positive airway pressure is recommended for the signs and symptoms of sleep apnea.

• For glucocorticoid-suppressible hyperaldosteronism: Low-dose glucocorticoid.


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