What are the common lab abnormalities in mixed cryoglobulinemic vasculitis?
Elevated RF and hypocomplementemia are seen in almost all patients with MC. Notably, C4 is reduced out of proportion to C3. A polyclonal hypergammaglobulinemia or monoclonal gammopathy are also frequently seen. Autoantibodies (other than RF) are seen in more than half of patients and include antinuclear, antismooth muscle, ANCA, antithyroid, antimitochondrial, and antiphospholipid antibodies.
