Is there any pattern to infections that occur post kidney transplantation

Is there any pattern to infections that occur post kidney transplantation?

Yes. Karuthu et al. reviewed this recently, including the timing of infections post transplant. Infections occur in a generally predictable pattern after kidney transplantation.

  • • First month post transplant:
    • • Nosocomial and surgery-related infections are the predominant infections
    • • Aspiration pneumonia
    • • Catheter infections
    • • Wound infections
    • • Anastomotic leaks
    • • Clostridium difficile colitis
    • • Resistant organisms such as methicillin-resistant Staphylococcus aureus
  • • Months post transplantation 1 through 6:
    • • Activation of latent infections is most common
    • • Pneumocystis jiroveci (previously Pneumocystis carinii ) pneumonia
    • • Fungal infections
    • • Herpes-related disease
    • • BK virus
    • • Clostridium difficile colitis
    • • Hepatitis C virus
    • • Adenovirus
    • • Influenza
    • • C ryptococcus
    • • Mycobacterium tuberculosis .
  • • Posttransplant month 6 and beyond:
    • • Community-acquired infections are predominant (urinary tract infections [UTIs], pneumonia)
    • • Fungal infections, including Nocardia, Aspergillus, and Mucor
    • • Late viral infections (cytomegalovirus [CMV], hepatitis B and C, herpes simplex virus, John Cunningham (JC) virus)
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