Is life expectancy altered by hypopituitarism

Is life expectancy altered by hypopituitarism?

All-cause mortality and vascular death are increased in patients with hypopituitarism compared with age- and gender-matched controls. A recent meta-analysis concluded that the standardized mortality ratio associated with hypopituitarism in men is 2.06 (95% confidence interval [CI], 1.94–2.20] and in women is 2.80 (95% CI, 2.59–3.02). Pituitary irradiation seems to confer an increased risk of death from cerebrovascular disease.

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