Is life expectancy altered by hypopituitarism?
- All-cause mortality and vascular death are increased in patients with hypopituitarism compared with age- and gender-matched controls.
- A recent meta-analysis concluded that the standardized mortality ratio associated with hypopituitarism in men is 2.06 (95% confidence interval [CI], 1.94–2.20] and in women is 2.80 (95% CI, 2.59–3.02).
- Pituitary irradiation seems to confer an increased risk of death from cerebrovascular disease.
