4 Interesting Facts of Idiopathic juvenile osteoporosis
- Mechanism unknown for this transient osteoporosis; typically lasts 3 to 5 years, with onset before puberty
- History of frequent fractures and bone pain
- Classically presents with pain in lower back, hips, feet, knee, and ankle; often accompanied by difficulty walking and limp
- Metaphyseal fractures and vertebral fractures are characteristic
- No extraskeletal manifestations or family history of osteogenesis imperfecta
- Genetic testing or bone biopsy will confirm diagnosis if unclear based on history and physical examination
- Decreased volume, mass, and thickness of trabecular bone on histomorphometry
