Idiopathic juvenile osteoporosis

4 Interesting Facts of Idiopathic juvenile osteoporosis

  1. Mechanism unknown for this transient osteoporosis; typically lasts 3 to 5 years, with onset before puberty
  2. History of frequent fractures and bone pain
    • Classically presents with pain in lower back, hips, feet, knee, and ankle; often accompanied by difficulty walking and limp
    • Metaphyseal fractures and vertebral fractures are characteristic
  3. No extraskeletal manifestations or family history of osteogenesis imperfecta
  4. Genetic testing or bone biopsy will confirm diagnosis if unclear based on history and physical examination 
    • Decreased volume, mass, and thickness of trabecular bone on histomorphometry

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