How useful are methylated folate and B12 based medicines

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How useful are methylated folate and B12 based medicines

Is there an advantage to using methylated folate and B12 products? 

Some individuals have a deficiency in methylene folate reductase activity in the CNS.

The use of methylated folate is required to circumvent this problem. Pharmacogenetic testing is available to determine if an individual has this polymorphism 

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