How the risk of skin cancer be reduced in patients who have received kidney transplant?
All kidney transplant recipients, especially those who have fair skin, live in sun-exposed climates, had significant sun exposure as a child, or have a history of skin cancer, should be educated on their high risk of skin cancer.
Minimization of sun exposure (avoiding the sun from 10 a.m. to 4 p.m.), the use of sunscreen, and meticulous skin self-examinations should be instituted to reduce the risk of skin cancers in this high-risk population.
An annual skin examination by a dermatologist is recommended in most kidney transplant recipients. In regard to immunosuppression, those on calcineurin inhibitor (CNI) converted to mechanistic target of rapamycin (mTOR) inhibitors have decreased rates of skin malignancies compared with those who remain on CNI. However, there is increased risk of rejection, and not all patients are able to tolerate the mTOR inhibitors.