How should endoscopic surveillance be performed in patients with UC and Crohn’s disease

How should endoscopic surveillance be performed in patients with UC and Crohn’s disease? 

  • Surveillance colonoscopy should be performed in patients with UC or extensive Crohn’s disease every 1 to 2 years beginning 8 to 10 years after the clear onset of disease symptoms.
  • During the colonoscopy, four-quadrant biopsy samples should be obtained every 10 cm from the cecum to the rectum (minimum of 32 biopsy samples) in these patients.
  • Biopsies targeted at macroscopically involved segments may be adequate for endoscopic surveillance in patients with less extensive colitis.
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