How often is iron deficiency anemia caused by underlying chronic GI blood loss?
Approximately 60% of persons with iron deficiency will have an identifiable cause detected by EGD and colonoscopy:
- • EGD demonstrates 36% (11% duodenal ulcer, 5% gastric ulcer, 3% anastomotic ulcer).
- • Colonoscopy demonstrates 25% (cancer was most common cause).
- • Diagnostic investigations should always be directed by symptoms and signs.
Non-GI causes should be considered as a potential cause of iron deficiency:
• Celiac disease
• Menstrual bleeding
• Nutritional deficiencies