How likely is Minimal change disease to be the cause of nephrotic syndrome in any individual?
Minimal change disease is the cause of nephrotic syndrome in approximately 90% of children younger than age 6, in approximately 65% of older children, and in approximately 20% to 30% of adolescents.
In adults with primary glomerular diseases, only 10% to 25% of nephrotic syndrome results from Minimal change disease, which puts it third after membranous nephropathy and focal, segmental glomerulosclerosis.