How is synovial sarcoma treated? What is the prognosis?
Treatment involves an aggressive combination of radical surgery, radiation therapy, and chemotherapy. Prognosis depends in large part on tumor stage at the time of discovery, age of patient (<25 years old do better), sex (females have a survival advantage), and whether or not the tumor is poorly differentiated. The cause of death in progressive disease is usually due to extensive pulmonary metastasis. Other common sites of metastasis include regional lymph nodes, bones, liver, skin, and brain.