How does FDG PET scan help with the diagnosis of myocardial sarcoidosis?
Granulomatous disease related to sarcoidosis typically is very FDG avid. Sarcoidosis can therefore easily be detected in affected areas of the body such as lymph nodes and lungs via FDG PET. In addition, FDG uptake in the heart itself may be seen and is suggestive of involvement by sarcoidosis. Typically, the patient is prepared for the study by either prolonged fasting or by eating a diet high in fat in order to reduce normal FDG uptake by the myocardium. The result is that myocardial uptake is low unless there is involvement by sarcoidosis, in which case heterogeneously increased FDG uptake in the myocardium is usually seen