How does abnormal serum magnesium cause hypocalcemia

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How does abnormal serum magnesium cause hypocalcemia?

• Magnesium levels below 1 mg/dL produce PTH resistance. With more severe hypomagnesemia, the secretion of PTH can also be impaired. Correction of the hypocalcemia requires first restoring magnesium.

• Magnesium levels over 6 mg/dL can suppress PTH secretion causing hypocalcemia.

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