How can synovial tissue be obtained?

How can synovial tissue be obtained?

MethodSize of Hole
Closed-needle biopsy +/– ultrasound (Parker Pearson or Tru-Cut needle)14-gauge needle (2.1 mm)
Ultrasound-guided forceps biopsy2.1 mm
Needle arthroscopy +/– ultrasound1.9, 2.7, 4.5 mm
Arthroscopy4 to 5 mm
Open surgical biopsySeveral inches
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