Genes commonly implicated in brain overgrowth syndromes
- PIK3CA
- AKT1
- AKT3
- MTOR
- PTEN
- TSC1 and TSC2
- FGFR2 and FGFR3
These genes are all part of the receptor tyrosine kinase (RTK)–phosphatidylinositol-3-kinase (PI3K)–AKT signaling pathway, which is an important regulator of cell growth.
Related Posts
-
Contiguous gene syndromesContiguous gene syndromes What is the concept of contiguous gene syndromes. Contiguous gene syndromes are…
-
-
Common genetic epileptic syndromesCommon genetic epileptic syndromes 1. Febrile convulsions2. Benign childhood epilepsy with centrotemporal spikes3. Childhood absence epilepsy4. Juvenile myoclonic epilepsy…
-
