What enteric infection has been associated with GBS?
- Respiratory and intestinal infections, vaccinations, and other immunologic influences have been associated with GBS, an autoimmune demyelinating or axonal peripheral neuropathy usually manifesting as progressive ascending weakness and paralysis.
- Campylobacter jejuni infection is the most common infection associated with GBS and is usually of an axonal subtype.
- Molecular mimicry of the bacterial lipopolysaccharide and ganglioside moieties on peripheral nerves appears to be a dominant mechanism.
- In the developing world, it is estimated that one third of all cases of acute flaccid paralysis are GBS caused by Campylobacter.
