What is the significance of Campylobacter jejuni infection in GBS?
Most patients (75%) with Guillain Barre syndrome and a preceding C. jejuni infection present with AIDP and often the axonal form.
Not all patients with serologic evidence of C. jejuni have gastrointestinal symptoms before the onset of GBS.
Cross-reactivity due to molecular mimicry between antigens from C. jejuni and various peripheral nerve gangliosides may explain the pathogenetic connection between the infection and GBS.