Significance of Campylobacter jejuni infection in GBS

What is the significance of Campylobacter jejuni infection in GBS? 

Most patients (75%) with Guillain Barre syndrome and a preceding C. jejuni infection present with AIDP and often the axonal form.

Not all patients with serologic evidence of C. jejuni have gastrointestinal symptoms before the onset of GBS.

Cross-reactivity due to molecular mimicry between antigens from C. jejuni and various peripheral nerve gangliosides may explain the pathogenetic connection between the infection and GBS.

15585

Sign up to receive the trending updates and tons of Health Tips

Join SeekhealthZ and never miss the latest health information

15856