Congenitally corrected transposition of the great vessels

What is congenitally corrected transposition of the great vessels, and why is it a problem?

In congenitally corrected transposition of the great vessels (l-TGV), there is an abnormal (L) ventricular loop, but there is also an abnormal (−150 degree) rotation of the great vessels. This leads to the following circuits: (1) systemic venous return-right atrium-left ventricle-pulmonary artery and (2) pulmonary venous return-left atrium-right ventricle-aorta. Although systemic and pulmonary blood flow circuits are “corrected” congenitally, this places abnormal stress on the right ventricle, which must pump blood against systemic pressures.

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