Commonly used radiopharmaceutical therapies

What are some commonly used radiopharmaceutical therapies?

Here is the table which lists some of the most common currently available radiopharmaceuticals as well as their approval status in the US.

Selected Therapeutic Radiopharmaceuticals

RADIOPHARMACEUTICALISOTOPEPRIMARY EMISSION(S)HALF-LIFEROUTE OF ADMINISTRATIONINDICATIONUS STATUS
Iodine-131 sodium iodide131 IBeta
Gamma
8 daysOralThyroid disease (thyroid cancer and hyperthyroidism)Approved
Yttrium-90 microspheres90 YBeta64 hoursIntra-arterial (hepatic artery)Hepatocellular carcinoma
Liver metastases
Approved
Yttrium-90 ibritumomab tiuxetan90 YBeta64 hoursIntravenousNon-Hodgkin lymphomaApproved
Radium-223 dichloride223 RaAlpha11.4 daysIntravenousBone dominant castrate-resistant prostate cancerApproved
Samarium-153 EDTMP153 SmBeta
Gamma
46.3 hoursIntravenousPainful bone metastasesApproved
Yttrium-90 or lutetium-177 somatostatin analogues (e.g., DOTATOC, DOTATATE)90 Y
177 Lu
Beta
Beta
Gamma
64 hours
6.6 days
IntravenousCarcinoid tumor
Pancreatic neuroendocrine tumor
Investigational
Iodine-131 MIBG131 IBeta
Gamma
8 daysIntravenousPheochromocytoma
Paraganglioma
Neuroendocrine tumor
Investigational
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