Clinical Features of Mixed Connective Tissue Disease

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Clinical Features of Mixed Connective Tissue Disease

Clinical ManifestationFrequency (%)

  • Arthritis/arthralgias
    • Jaccoud’s arthropathy
    • Erosions
  • Swollen hands and puffy fingers
  • Raynaud’s phenomenon
    • Nailfold capillary changes
  • Esophageal dysmotility
  • Mucocutaneous lesions
    • Sclerodermatous changes
    • Skin rash
    • Mouth sores
  • Muscle involvement
  • Lymphadenopathy
  • Fever
  • Serositis
  • Hepatosplenomegaly
  • Trigeminal neuralgia
  • Renal disease (membranous glomerulonephritis)
  • Myocarditis
  • Hypertensive crisis
  • Aseptic meningitis

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