Cause of death in acromegaly

What is the cause of death in patients with acromegaly?

  • Acromegaly increases cardiovascular and metabolic risk factors, including hypertension, glucose intolerance, cardiomyopathy, and sleep apnea.
  • The mortality from inadequately treated acromegaly is about double the expected rate in healthy age-matched subjects.
  • Major causes of death include hypertension, cardiovascular disease, heart failure, and diabetes.
  • Improved treatment has decreased this risk, but there is still a 30% increased risk of mortality in patients with acromegaly.
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