Can infection with GAS result in arthritis distinct from Acute Rheumatic Fever?
Possibly. A distinct phenotype of arthritis following GAS infection, without associated carditis and other ARF manifestations, is termed poststreptococcal reactive arthritis (PSRA) . The nonmigratory arthritis of PSRA occurs after a shorter latent period than typical ARF, but lasts longer than that of typical ARF (often months). Epidemiologically, PRSA most commonly affects young adults rather than children (with some studies arguing for a female predominance).