What is the blood pressure goal in the acute phase of Intracerebral Hemorrhage?
The 2010 AHA Stroke Council Guidelines recommended to keep blood pressure <160/90 mm Hg or MAP <110 mm Hg.
However, data from the INTERACT trial suggested that intensive systolic blood pressure lowering to <140 mm Hg is safe and was associated with better functional outcome on ordinal analysis of modified Rankin scale scores.
In practice, many neurointensivists recommend keeping systolic blood pressure <140 mm Hg pending the results of ongoing ATACH 2 phase 3 clinical trials comparing intensive blood pressure lowering (<140 mm Hg) versus standard blood pressure (<180 mm Hg).