Acquired causes of hyperuricemia

What are the acquired causes of hyperuricemia?

Urate overproduction: excess dietary purine consumption, accelerated hepatic ATP degradation in alcohol abuse or fructose ingestion, and increased nucleotide turnover in myeloproliferative and lymphoproliferative disorders.

Urate underexcretion: renal disease, lead nephropathy (saturnine gout), inhibition of tubular urate secretion (keto- and lactic acidosis), select drugs (see Question 9), and miscellaneous causes such as hyperparathyroidism, hypothyroidism, and respiratory acidosis.

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