What steroid sparing disease modifying antirheumatic drugs and biologics can be used in Polymyalgia Rheumatica

What steroid sparing disease modifying antirheumatic drugs and biologics can be used in Polymyalgia Rheumatica?

In patients with steroid-dependent PMR, MTX (10–20 mg/week) is reported to facilitate tapering of steroids. Azathioprine may also serve as a steroid-sparing agent. In 2016, Lally et al reported tocilizumab to be an effective treatment, highlighting the prominent role for IL-6 in the pathogenesis of PMR with higher remission rates, lower cumulative and shorter duration of GC therapy.

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