Facts of Polymyalgia Rheumatica

Facts of Polymyalgia Rheumatica

Polymyalgia Rheumatica is an inflammatory syndrome of older individuals characterized by pain and stiffness in the proximal muscles of the shoulder, neck, and/or pelvic girdle in the absence of objective weakness. Constitutional symptoms are common (33%–50% of patients). The core manifestations include:

  • • Patient age ≥50 years.
  • • Symmetric shoulder girdle aching for ≥2 weeks.
  • • ESR >40 mm/hour and/or elevated C-reactive protein (CRP).
  • • Morning stiffness >45 minutes.
  • • Bilateral hip pain or limited range of motion.
  • • Absence of rheumatoid factor (RF) and antibodies to citrullinated antigens (ACPAs).
  • • Rapid response to corticosteroids (prednisone 20 mg daily) within a week.
  • • Exclusion of other diagnoses except GCA

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