Role of long term antibiotics in enteric Reactive Arthritis

Role of long term antibiotics in enteric Reactive Arthritis

Should long term antibiotics be used in enteric Reactive Arthritis?

No. Antibiotic therapy for common postenteric-associated ReA has not been demonstrated in trials to reduce the severity of arthritis. The demonstration of bacterial cell wall antigens, but not nucleic acid in the synovial tissue, suggests that bacterial antigens alone (not viable microorganisms) may perpetuate this type of ReA and therefore antibiotics are not effective.

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