What is Rimexolone

Rimexolone is a corticosteroid that is administered topically to the eye to reduce inflammation during the postoperative period following ocular surgery. It is the first ophthalmic steroid indicated for this condition.

Rimexolone is also indicated for the treatment of anterior uveitis. In clinical studies, 1% rimexolone demonstrated clinical equivalence to 1% prednisolone in reducing uveitic inflammation.

Rimexolone was approved for ophthalmic use by the FDA on December 30, 1994.

A parenteral formulation is under investigation for intra-articular use in patients with rheumatoid arthritis.

Brand Name



  • postoperative ocular inflammation
  • rheumatoid arthritis
  • uveitis
  • vernal keratoconjunctivitis

Side Effects

  1. blurred vision
  2. cataracts
  3. corneal edema
  4. corneal erosion
  5. dysgeusia
  6. foreign body sensation
  7. headache
  8. hyperemia
  9. hypotension
  10. keratitis
  11. ocular discharge
  12. ocular hypertension
  13. ocular infection
  14. ocular irritation
  15. ocular pain
  16. ocular pruritus
  17. pharyngitis
  18. photophobia
  19. rhinitis
  20. visual impairment
  21. xerophthalmia

Monitoring Parameters

  • intraocular pressure


  • breast-feeding
  • cataracts
  • children
  • corticosteroid hypersensitivity
  • fungal infection
  • glaucoma
  • herpes simplex keratitis (dendritic keratitis)
  • infants
  • infection
  • mycobacterial infection
  • neonates
  • pregnancy
  • varicella
  • viral infection
  • visual disturbance


There are no drug interactions associated with Rimexolone products.


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