Respiratory Syncytial Virus Immune Globulin RSV IGIV

What is Respiratory Syncytial Virus Immune Globulin RSV IGIV

RespiGam(TM) (RSV IGIV), formerly known as Respivir(TM), is a polyclonal human hyperimmune globulin.

It is used to prevent lower respiratory syncytial virus (RSV) disease in high-risk children under 24 months of age with bronchopulmonary dysplasia (BPD) or chronic lung disease, or in infants with a history of premature birth.

Brand Name

RespiGam

Indications

  • respiratory syncytial virus (RSV) infection prophylaxis

For respiratory syncytial virus (RSV) infection prophylaxis in pediatric patients at high risk of RSV disease

Side Effects

  1. abdominal pain
  2. anaphylactoid reactions
  3. angioedema
  4. anxiety
  5. arthralgia
  6. aseptic meningitis
  7. cough
  8. cyanosis
  9. diarrhea
  10. dizziness
  11. drowsiness
  12. dyspnea
  13. edema
  14. fever
  15. flushing
  16. hypertension
  17. infection
  18. myalgia
  19. nausea
  20. pallor
  21. palpitations
  22. pruritus
  23. pulmonary edema
  24. rhinorrhea
  25. tachypnea
  26. vomiting
  27. wheezing

Monitoring Parameters

  • laboratory monitoring not necessary

Contraindications

  • acquired immunodeficiency syndrome (AIDS)
  • albumin hypersensitivity
  • breast-feeding
  • congenital heart disease
  • geriatric
  • hepatic disease
  • hypervolemia
  • IgA deficiency
  • immunosuppression
  • pregnancy
  • renal disease
  • renal impairment

Interactions

  • Measles Virus; Mumps Virus; Rubella Virus; Varicella Virus Vaccine, Live
  • Varicella-Zoster Virus Vaccine, Live
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