Pyridoxine Vitamin B6 Brand Name– Neuro-K-500
What is Pyridoxine Vitamin B6
Pyridoxine vitamin B6 is a naturally occurring, water-soluble vitamin found in food such as cereal grains, legumes, vegetables, liver, meat, and eggs.
Pyridoxine is used to treat and prevent vitamin B6 deficiency; to prevent or treat toxicity from isoniazid, cycloserine, or hydralazine; and to treat sideroblastic anemia associated with elevated serum iron levels.
It also has been used in pyridoxine-dependent neonates to treat seizures that are unresponsive to conventional therapy and in patients with metabolic disorders such as xanthurenic aciduria, primary hyperoxaluria, primary cystathioninuria, and primary homocystinuria.
Pyridoxine hydrochloride has been commercially available since approval by the FDA in 1940.
Indications
- cycloserine overdose
- cycloserine toxicity
- cycloserine toxicity prophylaxis
- cystathioninuria
- drug-induced seizures
- homocystinuria
- hydralazine toxicity
- hydralazine toxicity prophylaxis
- hyperoxaluria
- isoniazid overdose
- isoniazid toxicity
- isoniazid toxicity prophylaxis
- mushroom poisoning
- neuritis
- nutritional supplementation
- oral contraceptive toxicity prophylaxis
- penicillamine toxicity
- penicillamine toxicity prophylaxis
- pregnancy-induced nausea/vomiting
- premenstrual syndrome (PMS)
- pyridoxine-dependent seizures
- sideroblastic anemia
- vitamin B6 deficiency
- xanthurenic aciduria
Side Effects
- ataxia
- hyperesthesia
- metabolic acidosis
- nausea
- paresthesias
- peripheral neuropathy
- seizures
- vomiting
Monitoring Parameters
- CBC
Contraindications
- breast-feeding
- pregnancy
- premature neonates
- renal impairment
Interactions
- Abacavir; Dolutegravir; Lamivudine
- Aliskiren; Amlodipine; Hydrochlorothiazide, HCTZ
- Aliskiren; Hydrochlorothiazide, HCTZ
- Altretamine
- Amiloride; Hydrochlorothiazide, HCTZ
- Amlodipine; Hydrochlorothiazide, HCTZ; Olmesartan
- Amlodipine; Hydrochlorothiazide, HCTZ; Valsartan
- Aspirin, ASA; Citric Acid; Sodium Bicarbonate
- Atenolol
- Atenolol; Chlorthalidone
- Atropine; Hyoscyamine; Phenobarbital; Scopolamine
- Azilsartan; Chlorthalidone
- Belladonna Alkaloids; Ergotamine; Phenobarbital
- Benazepril; Hydrochlorothiazide, HCTZ
- Bendroflumethiazide; Nadolol
- Betamethasone; Calcipotriene
- Bictegravir; Emtricitabine; Tenofovir Alafenamide
- Bisoprolol; Hydrochlorothiazide, HCTZ
- Bisphosphonates
- Calcipotriene
- Calcitonin
- Calcium Phosphate, Supersaturated
- Candesartan; Hydrochlorothiazide, HCTZ
- Captopril; Hydrochlorothiazide, HCTZ
- Carbidopa; Levodopa
- Carbidopa; Levodopa; Entacapone
- Cardiac glycosides
- Chlorothiazide
- Chlorthalidone
- Chlorthalidone; Clonidine
- Ciprofloxacin
- Colesevelam
- Conjugated Estrogens
- Conjugated Estrogens; Bazedoxifene
- Conjugated Estrogens; Medroxyprogesterone
- Cycloserine
- Delafloxacin
- Dichlorphenamide
- Dienogest; Estradiol valerate
- Diethylstilbestrol, DES
- Dolutegravir
- Dolutegravir; Lamivudine
- Dolutegravir; Rilpivirine
- Drospirenone; Estradiol
- Drospirenone; Ethinyl Estradiol
- Drospirenone; Ethinyl Estradiol; Levomefolate
- Edetate Calcium Disodium, Calcium EDTA
- Edetate Disodium, Disodium EDTA
- Elagolix; Estradiol; Norethindrone acetate
- Eltrombopag
- Enalapril; Hydrochlorothiazide, HCTZ
- Eprosartan; Hydrochlorothiazide, HCTZ
- Esterified Estrogens
- Esterified Estrogens; Methyltestosterone
- Estradiol
- Estradiol Cypionate; Medroxyprogesterone
- Estradiol; Levonorgestrel
- Estradiol; Norethindrone
- Estradiol; Norgestimate
- Estradiol; Progesterone
- Estramustine
- Estrogens
- Estropipate
- Ethanol
- Ethinyl Estradiol
- Ethinyl Estradiol; Desogestrel
- Ethinyl Estradiol; Ethynodiol Diacetate
- Ethinyl Estradiol; Etonogestrel
- Ethinyl Estradiol; Levonorgestrel
- Ethinyl Estradiol; Levonorgestrel; Ferrous bisglycinate
- Ethinyl Estradiol; Levonorgestrel; Folic Acid; Levomefolate
- Ethinyl Estradiol; Norelgestromin
- Ethinyl Estradiol; Norethindrone
- Ethinyl Estradiol; Norethindrone Acetate
- Ethinyl Estradiol; Norethindrone Acetate; Ferrous fumarate
- Ethinyl Estradiol; Norethindrone; Ferrous fumarate
- Ethinyl Estradiol; Norgestimate
- Ethinyl Estradiol; Norgestrel
- Ethotoin
- Fosinopril; Hydrochlorothiazide, HCTZ
- Fosphenytoin
- Gallium
- Hydralazine; Hydrochlorothiazide, HCTZ
- Hydrochlorothiazide, HCTZ
- Hydrochlorothiazide, HCTZ; Irbesartan
- Hydrochlorothiazide, HCTZ; Lisinopril
- Hydrochlorothiazide, HCTZ; Losartan
- Hydrochlorothiazide, HCTZ; Methyldopa
- Hydrochlorothiazide, HCTZ; Metoprolol
- Hydrochlorothiazide, HCTZ; Moexipril
- Hydrochlorothiazide, HCTZ; Olmesartan
- Hydrochlorothiazide, HCTZ; Propranolol
- Hydrochlorothiazide, HCTZ; Quinapril
- Hydrochlorothiazide, HCTZ; Spironolactone
- Hydrochlorothiazide, HCTZ; Telmisartan
- Hydrochlorothiazide, HCTZ; Triamterene
- Hydrochlorothiazide, HCTZ; Valsartan
- Ibritumomab Tiuxetan
- Levodopa
- Levofloxacin
- Mestranol; Norethindrone
- Methyclothiazide
- Metolazone
- Moxifloxacin
- Neuromuscular blockers
- Norfloxacin
- Ofloxacin
- Omeprazole; Sodium Bicarbonate
- Penicillamine
- Phenobarbital
- Phenytoin
- Phosphorated Carbohydrate Solution
- Phosphorus
- Potassium Phosphate
- Potassium Phosphate; Sodium Phosphate
- Segesterone Acetate; Ethinyl Estradiol
- Sodium Bicarbonate
- Sodium Fluoride
- Sodium Phosphate Monobasic Monohydrate; Sodium Phosphate Dibasic Anhydrous
- Tetracyclines
- Thiazide diuretics
- Thyroid hormones
- Trientine
- Vitamin A
- Vitamin D analogs
