pegloticase

What is pegloticase?

In contrast with other mammals, homo sapiens (and other higher primates) lack uricase, an enzyme which converts uric acid to the more soluble allantoin. Pegloticase is a recombinant mammalian uricase attached to polyethylene glycol (PEGylated). Due to cost (∼2000 $US per infusion) and risk of adverse events, it is recommended for cases with severe disease burden and either intolerance of usual ULT or refractory disease despite appropriate dosing of usual ULT.

15585

Sign up to receive the trending updates and tons of Health Tips

Join SeekhealthZ and never miss the latest health information

15856