Naphazoline and Pheniramine

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Naphazoline and Pheniramine Brand Names

AK-Con-A | Naphcon-A | Opcon-A | Visine Multi-Action Eye Allergy Relief | Visine-A

What is Naphazoline and Pheniramine

Naphazoline and pheniramine are used together in an ophthalmic preparation for the temporary relief of ocular pruritus and redness due to common allergens (i.e., ragweed, pollen, grass, animal hair and dander).

Naphazoline’s decongestant activity decreases the ocular inflammation and redness. Pheniramine is an H1-blocker that reduces ocular itching and congestion.


  • conjunctival hyperemia
  • ocular pruritus

For the temporary relief of ocular pruritus and conjunctival hyperemia caused by pollen, ragweed, grass, and animal hair and dander

Side Effects

  • conjunctival hyperemia
  • ocular irritation
  • ocular pain

Advise patients to discontinue use of naphazoline; pheniramine if ocular pain or ocular irritation occurs or if symptoms worsen or persist longer than 72 hours. Overuse of naphazoline; pheniramine may result in increased conjunctival hyperemia.

Monitoring Parameters

  • laboratory monitoring not necessary


  • breast-feeding
  • cardiac disease
  • children
  • closed-angle glaucoma
  • contact lenses
  • hypertension
  • infants
  • pregnancy
  • prostatic hypertrophy


There are no drug interactions associated with Naphazoline; Pheniramine products.

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