Nandrolone Decanoate Brand Name– Deca-Durabolin
What is Nandrolone Decanoate
Nandrolone decanoate is a parenteral anabolic steroid. It is used to manage the anemia of chronic renal failure and for osteoporosis.
This agent will increase hemoglobin and red cell mass. With the development of recombinant human erythropoietin, nandrolone decanoate use in anemia associated with chronic renal failure has declined.
Data on the effects of combining nandrolone decanoate and epoetin alfa are lacking. Anabolic steroids also promote body tissue-building processes and reverse catabolic or tissue-depleting processes.
They have also been the subject of drug misuse and abuse, often producing adverse effects such as changes in libido, hepatotoxicity, increased risk of cardiovascular disease, and antisocial behavior.
Some of the masculinizing effects in women can be irreversible. When using androgens and anabolic steroids, it is important to provide adequate calorie and protein intake to maintain a positive nitrogen balance.
Nandrolone decanoate was approved by the FDA in 1983 and became a controlled substance in 1991.
Indications
- AIDS-associated wasting syndrome
- anemia
- cachexia
- osteoporosis
For the treatment of anemia associated with chronic renal failure
Side Effects
- acne vulgaris
- acneiform rash
- alopecia
- amenorrhea
- clitoromegaly
- decreased ejaculate volume
- depression
- diarrhea
- elevated hepatic enzymes
- epididymitis
- epiphyseal closure
- excitability
- feminization
- fluid retention
- gynecomastia
- hepatic failure
- hepatic necrosis
- hepatitis
- hirsutism
- hoarseness
- hypercalcemia
- hypercholesterolemia
- impotence (erectile dysfunction)
- injection site reaction
- insomnia
- jaundice
- libido decrease
- libido increase
- mastalgia
- menstrual irregularity
- nausea
- new primary malignancy
- oligomenorrhea
- oligospermia
- peliosis hepatis
- penile enlargement
- peripheral edema
- priapism
- prolonged bleeding time
- prostatic hypertrophy
- sodium retention
- teratogenesis
- testicular atrophy
- tumorigenicity
- virilization
- vomiting
- weight gain
Monitoring Parameters
- LFTs
Contraindications
- arteriosclerosis
- benzyl alcohol hypersensitivity
- breast cancer
- breast-feeding
- cardiac disease
- children
- cholestasis
- coronary artery disease
- diabetes mellitus
- heart failure
- hepatic disease
- hypercalcemia
- hypercholesterolemia
- intravenous administration
- jaundice
- myocardial infarction
- new primary malignancy
- peliosis hepatis
- peripheral edema
- pregnancy
- prostate cancer
- prostatic hypertrophy
- renal disease
- tumorigenicity
Interactions
- Abarelix
- Acarbose
- Alogliptin
- Alogliptin; Metformin
- Alogliptin; Pioglitazone
- Alpha-glucosidase Inhibitors
- Anticoagulants
- Canagliflozin
- Canagliflozin; Metformin
- Cyclosporine
- Dapagliflozin
- Dapagliflozin; Metformin
- Dapagliflozin; Saxagliptin
- Darbepoetin Alfa
- Degarelix
- Dipeptidyl Peptidase-4 Inhibitors
- Empagliflozin
- Empagliflozin; Linagliptin
- Empagliflozin; Linagliptin; Metformin
- Empagliflozin; Metformin
- Epoetin Alfa
- Ertugliflozin
- Ertugliflozin; Metformin
- Ertugliflozin; Sitagliptin
- Glipizide; Metformin
- Glyburide; Metformin
- Goserelin
- Histrelin
- Incretin Mimetics
- Insulins
- Leuprolide
- Leuprolide; Norethindrone
- Linagliptin
- Linagliptin; Metformin
- Meglitinides
- Metformin
- Metformin; Pioglitazone
- Metformin; Repaglinide
- Metformin; Rosiglitazone
- Metformin; Saxagliptin
- Metformin; Sitagliptin
- Methoxy polyethylene glycol-epoetin beta
- Miglitol
- Nafarelin
- Pramlintide
- Saw Palmetto, Serenoa repens
- Saxagliptin
- SGLT2 Inhibitors
- Simvastatin; Sitagliptin
- Sitagliptin
- Sulfonylureas
- Thiazolidinediones
- Triptorelin