Methylcellulose

Methylcellulose Brand Names

Citrucel | Fiber Therapy | Murocel

What is Methylcellulose

Methylcellulose is a synthetic, orally administered, bulk-forming laxative used in the treatment of constipation and diarrhea.

Methylcellulose is indicated for constipation that occurs in elderly patients as well as in patients with low-fiber diets, prolonged bed rest or hospitalization, pregnancy, colostomies, irritable bowel syndrome, or diverticular disease.

It is also indicated for control of diarrhea in patients with chronic watery diarrhea. The drug is commonly used in children aged 6 years and older.

Methylcellulose was originally approved by the FDA in 1942.

Indications

  • constipation
  • diarrhea
  • diverticulosis
  • irritable bowel syndrome

For treatment and prevention of constipation, as an adjunct for the management of irritable bowel syndrome or diverticulosis, or to aid in the management of chronic diarrhea

Side Effects

  1. abdominal pain
  2. asphyxia
  3. chest pain (unspecified)
  4. diarrhea
  5. GI obstruction
  6. nausea
  7. vomiting

Monitoring Parameters

  • laboratory monitoring not necessary

Contraindications

  • abdominal pain
  • acute abdomen
  • appendicitis
  • breast-feeding
  • dysphagia
  • esophageal stricture
  • geriatric
  • GI bleeding
  • GI obstruction
  • ileus
  • phenylketonuria
  • pregnancy
  • vomiting

Interactions

  • Atropine; Difenoxin
  • Atropine; Diphenoxylate
  • Bumetanide
  • Calcium Phosphate, Supersaturated
  • Dichlorphenamide
  • Ethacrynic Acid
  • Furosemide
  • Lactulose
  • Loop diuretics
  • Sodium Phosphate Monobasic Monohydrate; Sodium Phosphate Dibasic Anhydrous
  • Torsemide
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