Meloxicam

Meloxicam Brand Names

Anjeso | Mobic | Qmiiz | Vivlodex

What is Meloxicam

Meloxicam is an oral and parenteral nonsteroidal anti-inflammatory drug (NSAID) indicated for osteoarthritis, rheumatoid arthritis, or juvenile rheumatoid arthritis and for moderate or severe pain alone or in combination with other non-NSAID analgesics, respectively.

Because of delayed onset of action, IV meloxicam alone is not recommended for use when rapid onset of analgesia is required.

Meloxicam, like all NSAIDs, may exacerbate hypertension and congestive heart failure and may cause an increased risk of serious cardiovascular thromboembolism, acute myocardial infarction, and stroke, which can be fatal.

Also, serious gastrointestinal (GI) tract adverse effects, such as GI bleeding or inflammation and stomach or other GI perforation and ulceration, can occur without warning or symptoms in patients receiving NSAIDs.

The lowest effective meloxicam dose for the shortest possible duration consistent with individual treatment goals is recommended to minimize the potential risk for an adverse cardiovascular or GI event.

Indications

  1. juvenile rheumatoid arthritis (JRA)/juvenile idiopathic arthritis (JIA)
  2. moderate pain
  3. osteoarthritis
  4. rheumatoid arthritis
  5. severe pain

For the relief of the signs and symptoms of osteoarthritis

Side Effects

  1. abdominal pain
  2. agranulocytosis
  3. alopecia
  4. anaphylactic shock
  5. anaphylactoid reactions
  6. anemia
  7. angina
  8. angioedema
  9. anorexia
  10. anxiety
  11. appetite stimulation
  12. arrhythmia exacerbation
  13. arthralgia
  14. aseptic meningitis
  15. asthenia
  16. azotemia
  17. back pain
  18. bronchospasm
  19. bullous rash
  20. chest pain (unspecified)
  21. colitis
  22. confusion
  23. conjunctivitis
  24. constipation
  25. contact dermatitis
  26. cough
  27. cystitis
  28. dehydration
  29. depression
  30. diaphoresis
  31. diarrhea
  32. dizziness
  33. drowsiness
  34. dysgeusia
  35. dyspepsia
  36. dyspnea
  37. ecchymosis
  38. edema
  39. elevated hepatic enzymes
  40. epistaxis
  41. eructation
  42. erythema
  43. erythema multiforme
  44. esophageal ulceration
  45. esophagitis
  46. exfoliative dermatitis
  47. fatigue
  48. fever
  49. flatulence
  50. fluid retention
  51. gastritis
  52. gastroesophageal reflux
  53. GI bleeding
  54. GI perforation
  55. hallucinations
  56. headache
  57. heart failure
  58. hematemesis
  59. hematoma
  60. hematuria
  61. hepatic failure
  62. hepatic necrosis
  63. hepatitis
  64. hot flashes
  65. hyperbilirubinemia
  66. hypertension
  67. hyperthermia
  68. hypokalemia
  69. hypomagnesemia
  70. hyponatremia
  71. hypotension
  72. hypoxia
  73. increased urinary frequency
  74. infection
  75. infertility
  76. influenza
  77. injection site reaction
  78. insomnia
  79. interstitial nephritis
  80. jaundice
  81. laryngitis
  82. leukopenia
  83. maculopapular rash
  84. malaise
  85. melena
  86. migraine
  87. myocardial infarction
  88. nausea
  89. neutropenia
  90. oral ulceration
  91. palpitations
  92. pancreatitis
  93. paresthesias
  94. peptic ulcer
  95. peripheral edema
  96. pharyngitis
  97. photosensitivity
  98. pruritus
  99. purpura
  100. rash
  101. renal failure (unspecified)
  102. renal papillary necrosis
  103. seizures
  104. sinus tachycardia
  105. sinusitis
  106. Stevens-Johnson syndrome
  107. stomatitis
  108. stroke
  109. syncope
  110. thrombocytopenia
  111. thrombocytosis
  112. thromboembolism
  113. tinnitus
  114. tolerance
  115. toxic epidermal necrolysis
  116. tremor
  117. urinary retention
  118. urticaria
  119. vasculitis
  120. vertigo
  121. vomiting
  122. weight gain
  123. weight loss
  124. withdrawal
  125. wound dehiscence
  126. xerostomia

Monitoring Parameters

  • CBC
  • LFTs
  • serum creatinine/BUN

Contraindications

  • acute bronchospasm
  • acute myocardial infarction
  • alcoholism
  • anemia
  • angina
  • anticoagulant therapy
  • asthma
  • bone marrow suppression
  • breast-feeding
  • cardiac arrhythmias
  • cardiac disease
  • cerebrovascular disease
  • coronary artery bypass graft surgery (CABG)
  • coronary artery disease
  • corticosteroid therapy
  • dehydration
  • geriatric
  • GI bleeding
  • GI disease
  • GI perforation
  • heart failure
  • hepatic disease
  • hypertension
  • hypovolemia
  • immunosuppression
  • infertility
  • jaundice
  • myocardial infarction
  • nasal polyps
  • neutropenia
  • NSAID hypersensitivity
  • peptic ulcer disease
  • peripheral edema
  • peripheral vascular disease
  • phenylketonuria
  • pregnancy
  • renal disease
  • renal failure
  • renal impairment
  • reproductive risk
  • salicylate hypersensitivity
  • stroke
  • tachycardia
  • thromboembolism
  • tobacco smoking
  • urticaria

Interactions

  • Abciximab
  • Acebutolol
  • Acetaminophen; Aspirin, ASA; Caffeine
  • Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
  • Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
  • Acetohexamide
  • Acyclovir
  • Adefovir
  • Aldesleukin, IL-2
  • Aliskiren
  • Aliskiren; Amlodipine
  • Aliskiren; Amlodipine; Hydrochlorothiazide, HCTZ
  • Aliskiren; Hydrochlorothiazide, HCTZ
  • Aliskiren; Valsartan
  • Alpha-blockers
  • Alteplase
  • Altretamine
  • Ambenonium Chloride
  • Amikacin
  • Amiloride
  • Amiloride; Hydrochlorothiazide, HCTZ
  • Aminolevulinic Acid
  • Aminosalicylate sodium, Aminosalicylic acid
  • Amiodarone
  • Amlodipine; Benazepril
  • Amlodipine; Celecoxib
  • Amlodipine; Hydrochlorothiazide, HCTZ; Olmesartan
  • Amlodipine; Hydrochlorothiazide, HCTZ; Valsartan
  • Amlodipine; Olmesartan
  • Amlodipine; Telmisartan
  • Amlodipine; Valsartan
  • Amphotericin B
  • Amphotericin B cholesteryl sulfate complex (ABCD)
  • Amphotericin B lipid complex (ABLC)
  • Amphotericin B liposomal (LAmB)
  • Anagrelide
  • Angiotensin II receptor antagonists
  • Angiotensin-converting enzyme inhibitors
  • Antithrombin III
  • Antithymocyte Globulin
  • Apixaban
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  • Aprotinin
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  • Aspirin, ASA
  • Aspirin, ASA; Butalbital; Caffeine
  • Aspirin, ASA; Butalbital; Caffeine; Codeine
  • Aspirin, ASA; Caffeine; Dihydrocodeine
  • Aspirin, ASA; Caffeine; Orphenadrine
  • Aspirin, ASA; Carisoprodol
  • Aspirin, ASA; Carisoprodol; Codeine
  • Aspirin, ASA; Citric Acid; Sodium Bicarbonate
  • Aspirin, ASA; Dipyridamole
  • Aspirin, ASA; Omeprazole
  • Aspirin, ASA; Oxycodone
  • Aspirin, ASA; Pravastatin
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  • Atropine; Edrophonium
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  • Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Disoproxil Fumarate
  • Emtricitabine
  • Emtricitabine; Rilpivirine; Tenofovir alafenamide
  • Emtricitabine; Rilpivirine; Tenofovir disoproxil fumarate
  • Emtricitabine; Tenofovir alafenamide
  • Emtricitabine; Tenofovir disoproxil fumarate
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  • Ethanol
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  • Flavocoxid, Flavocoxid; Citrated Zinc Bisglycinate
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  • Fluoxetine; Olanzapine
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  • Fluticasone; Salmeterol
  • Fluticasone; Umeclidinium; Vilanterol
  • Fluticasone; Vilanterol
  • Fluvastatin
  • Fluvoxamine
  • Fondaparinux
  • Formoterol; Mometasone
  • Foscarnet
  • Fosinopril
  • Fosinopril; Hydrochlorothiazide, HCTZ
  • Furosemide
  • Gadoterate meglumine
  • Galantamine
  • Gallium Ga 68 Dotatate
  • Ganciclovir
  • Garlic, Allium sativum
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  • Gentamicin
  • Ginger, Zingiber officinale
  • Ginkgo, Ginkgo biloba
  • Glimepiride
  • Glimepiride; Pioglitazone
  • Glimepiride; Rosiglitazone
  • Glipizide
  • Glipizide; Metformin
  • Glyburide
  • Glyburide; Metformin
  • Gold
  • grapefruit juice
  • Guanabenz
  • Guanfacine
  • Heparin
  • Hyaluronidase, Recombinant; Immune Globulin
  • Hydralazine
  • Hydralazine; Hydrochlorothiazide, HCTZ
  • Hydralazine; Isosorbide Dinitrate, ISDN
  • Hydrochlorothiazide, HCTZ; Irbesartan
  • Hydrochlorothiazide, HCTZ; Lisinopril
  • Hydrochlorothiazide, HCTZ; Losartan
  • Hydrochlorothiazide, HCTZ; Methyldopa
  • Hydrochlorothiazide, HCTZ; Metoprolol
  • Hydrochlorothiazide, HCTZ; Moexipril
  • Hydrochlorothiazide, HCTZ; Olmesartan
  • Hydrochlorothiazide, HCTZ; Propranolol
  • Hydrochlorothiazide, HCTZ; Quinapril
  • Hydrochlorothiazide, HCTZ; Spironolactone
  • Hydrochlorothiazide, HCTZ; Telmisartan
  • Hydrochlorothiazide, HCTZ; Triamterene
  • Hydrochlorothiazide, HCTZ; Valsartan
  • Hydrocodone; Ibuprofen
  • Hydrocortisone
  • Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
  • Ibritumomab Tiuxetan
  • Ibuprofen
  • Ibuprofen lysine
  • Ibuprofen; Oxycodone
  • Ibuprofen; Pseudoephedrine
  • Idelalisib
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  • Immune Globulin IV, IVIG, IGIV
  • Indapamide
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  • Irbesartan
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  • Kanamycin
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  • Labetalol
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  • Lansoprazole; Naproxen
  • Leflunomide
  • Lepirudin
  • Levobetaxolol
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  • Levomilnacipran
  • Lisinopril
  • Lithium
  • Lomustine, CCNU
  • Lopinavir; Ritonavir
  • Losartan
  • Lumacaftor; Ivacaftor
  • Lumacaftor; Ivacaftor
  • Macimorelin
  • Magnesium Salicylate
  • Magnesium Salts
  • Magnesium Sulfate; Potassium Sulfate; Sodium Sulfate
  • Mannitol
  • Mecamylamine
  • Mechlorethamine, Nitrogen Mustard
  • Meclofenamate Sodium
  • Mefenamic Acid
  • Melphalan
  • Mesalamine, 5-ASA
  • Methotrexate
  • Methoxsalen
  • Methyldopa
  • Methylprednisolone
  • Methylsulfonylmethane, MSM
  • Metoprolol
  • Mifepristone
  • Milnacipran
  • Minoxidil
  • Mitomycin
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  • Mitoxantrone
  • Modafinil
  • Moexipril
  • Mometasone
  • Muromonab-CD3
  • Nabumetone
  • Nadolol
  • Naproxen
  • Naproxen; Pseudoephedrine
  • Naproxen; Sumatriptan
  • Nebivolol
  • Nebivolol; Valsartan
  • Nelarabine
  • Neomycin
  • Neostigmine
  • Nitroprusside
  • Non-Ionic Contrast Media
  • Olmesartan
  • Omacetaxine
  • Ombitasvir; Paritaprevir; Ritonavir
  • Oritavancin
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  • Paclitaxel
  • Paroxetine
  • Pazopanib
  • Pegaspargase
  • Penbutolol
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  • Pentosan
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  • Perindopril
  • Perindopril; Amlodipine
  • Phenoxybenzamine
  • Phentermine; Topiramate
  • Phentolamine
  • Photosensitizing agents (topical)
  • Physostigmine
  • Pindolol
  • Piroxicam
  • Platelet Inhibitors
  • Pneumococcal Vaccine, Polyvalent
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  • Sodium Phosphate Monobasic Monohydrate; Sodium Phosphate Dibasic Anhydrous
  • Sodium picosulfate; Magnesium oxide; Anhydrous citric acid
  • Sodium Polystyrene Sulfonate
  • Sotalol
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