Meloxicam

Meloxicam Brand Names

Anjeso | Mobic | Qmiiz | Vivlodex

What is Meloxicam

Meloxicam is an oral and parenteral nonsteroidal anti-inflammatory drug (NSAID) indicated for osteoarthritis, rheumatoid arthritis, or juvenile rheumatoid arthritis and for moderate or severe pain alone or in combination with other non-NSAID analgesics, respectively.

Because of delayed onset of action, IV meloxicam alone is not recommended for use when rapid onset of analgesia is required.

Meloxicam, like all NSAIDs, may exacerbate hypertension and congestive heart failure and may cause an increased risk of serious cardiovascular thromboembolism, acute myocardial infarction, and stroke, which can be fatal.

Also, serious gastrointestinal (GI) tract adverse effects, such as GI bleeding or inflammation and stomach or other GI perforation and ulceration, can occur without warning or symptoms in patients receiving NSAIDs.

The lowest effective meloxicam dose for the shortest possible duration consistent with individual treatment goals is recommended to minimize the potential risk for an adverse cardiovascular or GI event.

Indications

1. juvenile rheumatoid arthritis (JRA)/juvenile idiopathic arthritis (JIA)
2. moderate pain
3. osteoarthritis
4. rheumatoid arthritis
5. severe pain

For the relief of the signs and symptoms of osteoarthritis

Side Effects

1. abdominal pain
2. agranulocytosis
3. alopecia
4. anaphylactic shock
5. anaphylactoid reactions
6. anemia
7. angina
8. angioedema
9. anorexia
10. anxiety
11. appetite stimulation
12. arrhythmia exacerbation
13. arthralgia
14. aseptic meningitis
15. asthenia
16. azotemia
17. back pain
18. bronchospasm
19. bullous rash
20. chest pain (unspecified)
21. colitis
22. confusion
23. conjunctivitis
24. constipation
25. contact dermatitis
26. cough
27. cystitis
28. dehydration
29. depression
30. diaphoresis
31. diarrhea
32. dizziness
33. drowsiness
34. dysgeusia
35. dyspepsia
36. dyspnea
37. ecchymosis
38. edema
39. elevated hepatic enzymes
40. epistaxis
41. eructation
42. erythema
43. erythema multiforme
44. esophageal ulceration
45. esophagitis
46. exfoliative dermatitis
47. fatigue
48. fever
49. flatulence
50. fluid retention
51. gastritis
52. gastroesophageal reflux
53. GI bleeding
54. GI perforation
55. hallucinations
56. headache
57. heart failure
58. hematemesis
59. hematoma
60. hematuria
61. hepatic failure
62. hepatic necrosis
63. hepatitis
64. hot flashes
65. hyperbilirubinemia
66. hypertension
67. hyperthermia
68. hypokalemia
69. hypomagnesemia
70. hyponatremia
71. hypotension
72. hypoxia
73. increased urinary frequency
74. infection
75. infertility
76. influenza
77. injection site reaction
78. insomnia
79. interstitial nephritis
80. jaundice
81. laryngitis
82. leukopenia
83. maculopapular rash
84. malaise
85. melena
86. migraine
87. myocardial infarction
88. nausea
89. neutropenia
90. oral ulceration
91. palpitations
92. pancreatitis
93. paresthesias
94. peptic ulcer
95. peripheral edema
96. pharyngitis
97. photosensitivity
98. pruritus
99. purpura
100. rash
101. renal failure (unspecified)
102. renal papillary necrosis
103. seizures
104. sinus tachycardia
105. sinusitis
106. Stevens-Johnson syndrome
107. stomatitis
108. stroke
109. syncope
110. thrombocytopenia
111. thrombocytosis
112. thromboembolism
113. tinnitus
114. tolerance
115. toxic epidermal necrolysis
116. tremor
117. urinary retention
118. urticaria
119. vasculitis
120. vertigo
121. vomiting
122. weight gain
123. weight loss
124. withdrawal
125. wound dehiscence
126. xerostomia

Monitoring Parameters

• CBC
• LFTs
• serum creatinine/BUN

Contraindications

• acute bronchospasm
• acute myocardial infarction
• alcoholism
• anemia
• angina
• anticoagulant therapy
• asthma
• bone marrow suppression
• breast-feeding
• cardiac arrhythmias
• cardiac disease
• cerebrovascular disease
• coronary artery bypass graft surgery (CABG)
• coronary artery disease
• corticosteroid therapy
• dehydration
• geriatric
• GI bleeding
• GI disease
• GI perforation
• heart failure
• hepatic disease
• hypertension
• hypovolemia
• immunosuppression
• infertility
• jaundice
• myocardial infarction
• nasal polyps
• neutropenia
• NSAID hypersensitivity
• peptic ulcer disease
• peripheral edema
• peripheral vascular disease
• phenylketonuria
• pregnancy
• renal disease
• renal failure
• renal impairment
• reproductive risk
• salicylate hypersensitivity
• stroke
• tachycardia
• thromboembolism
• tobacco smoking
• urticaria

Interactions

• Abciximab
• Acebutolol
• Acetaminophen; Aspirin, ASA; Caffeine
• Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
• Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
• Acetohexamide
• Acyclovir
• Adefovir
• Aldesleukin, IL-2
• Aliskiren
• Aliskiren; Amlodipine
• Aliskiren; Amlodipine; Hydrochlorothiazide, HCTZ
• Aliskiren; Hydrochlorothiazide, HCTZ
• Aliskiren; Valsartan
• Alpha-blockers
• Alteplase
• Altretamine
• Ambenonium Chloride
• Amikacin
• Amiloride
• Amiloride; Hydrochlorothiazide, HCTZ
• Aminolevulinic Acid
• Aminosalicylate sodium, Aminosalicylic acid
• Amiodarone
• Amlodipine; Benazepril
• Amlodipine; Celecoxib
• Amlodipine; Hydrochlorothiazide, HCTZ; Olmesartan
• Amlodipine; Hydrochlorothiazide, HCTZ; Valsartan
• Amlodipine; Olmesartan
• Amlodipine; Telmisartan
• Amlodipine; Valsartan
• Amphotericin B
• Amphotericin B cholesteryl sulfate complex (ABCD)
• Amphotericin B lipid complex (ABLC)
• Amphotericin B liposomal (LAmB)
• Anagrelide
• Angiotensin II receptor antagonists
• Angiotensin-converting enzyme inhibitors
• Antithrombin III
• Antithymocyte Globulin
• Apixaban
• Aprepitant, Fosaprepitant
• Aprotinin
• Argatroban
• Arsenic Trioxide
• Aspirin, ASA
• Aspirin, ASA; Butalbital; Caffeine
• Aspirin, ASA; Butalbital; Caffeine; Codeine
• Aspirin, ASA; Caffeine; Dihydrocodeine
• Aspirin, ASA; Caffeine; Orphenadrine
• Aspirin, ASA; Carisoprodol
• Aspirin, ASA; Carisoprodol; Codeine
• Aspirin, ASA; Citric Acid; Sodium Bicarbonate
• Aspirin, ASA; Dipyridamole
• Aspirin, ASA; Omeprazole
• Aspirin, ASA; Oxycodone
• Aspirin, ASA; Pravastatin
• Atazanavir
• Atazanavir; Cobicistat
• Atenolol
• Atenolol; Chlorthalidone
• Atropine; Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
• Atropine; Edrophonium
• Azathioprine
• Azelastine; Fluticasone
• Azilsartan
• Azilsartan; Chlorthalidone
• Bacitracin
• Beclomethasone
• Benazepril
• Benazepril; Hydrochlorothiazide, HCTZ
• Bendamustine
• Bendroflumethiazide; Nadolol
• Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
• Beta-blockers
• Betamethasone
• Betaxolol
• Betrixaban
• Bexarotene
• Bictegravir; Emtricitabine; Tenofovir Alafenamide
• Bismuth Subsalicylate
• Bismuth Subsalicylate; Metronidazole; Tetracycline
• Bisoprolol
• Bisoprolol; Hydrochlorothiazide, HCTZ
• Bisphosphonates
• Bivalirudin
• Bleomycin
• Boceprevir
• Brimonidine; Timolol
• Budesonide
• Budesonide; Formoterol
• Bumetanide
• Busulfan
• Calcium Phosphate, Supersaturated
• Calcium-channel blockers
• Candesartan
• Candesartan; Hydrochlorothiazide, HCTZ
• Cannabidiol
• Capecitabine
• Capreomycin
• Captopril
• Captopril; Hydrochlorothiazide, HCTZ
• Carmustine, BCNU
• Carteolol
• Carvedilol
• Cefotaxime
• Celecoxib
• Ceritinib
• Chlorambucil
• Chlorpropamide
• Chlorthalidone; Clonidine
• Cholestyramine
• Choline Salicylate; Magnesium Salicylate
• Cholinesterase inhibitors
• Ciclesonide
• Cidofovir
• Cilostazol
• Citalopram
• Cladribine
• Clofarabine
• Clonidine
• Clopidogrel
• Colchicine; Probenecid
• Colistimethate, Colistin, Polymyxin E
• Corticosteroids
• Cortisone
• Cyclosporine
• Cytarabine, ARA-C
• Dabigatran
• Dabrafenib
• Dacarbazine, DTIC
• Dactinomycin, Actinomycin D
• Dalteparin
• Danaparoid
• Darunavir
• Darunavir; Cobicistat
• Darunavir; Cobicistat; Emtricitabine; Tenofovir alafenamide
• Dasabuvir; Ombitasvir; Paritaprevir; Ritonavir
• Dasatinib
• Decitabine
• Deferasirox
• Deflazacort
• Delavirdine
• Denileukin Diftitox
• Desirudin
• Desmopressin
• Desvenlafaxine
• Dexamethasone
• Diazoxide
• Diclofenac
• Diclofenac; Misoprostol
• Diflunisal
• Diphenhydramine; Ibuprofen
• Diphenhydramine; Naproxen
• Dipyridamole
• Disulfiram
• Docetaxel
• Donepezil
• Donepezil; Memantine
• Doravirine; Lamivudine; Tenofovir disoproxil fumarate
• Dorzolamide; Timolol
• Doxazosin
• Dronedarone
• Drospirenone
• Drospirenone; Estradiol
• Drospirenone; Ethinyl Estradiol
• Drospirenone; Ethinyl Estradiol; Levomefolate
• Drotrecogin Alfa
• Duloxetine
• Edoxaban
• Edrophonium
• Efavirenz
• Efavirenz; Emtricitabine; Tenofovir
• Efavirenz; Lamivudine; Tenofovir Disoproxil Fumarate
• Elbasvir; Grazoprevir
• Elexacaftor; tezacaftor; ivacaftor
• Eltrombopag
• Elvitegravir
• Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Alafenamide
• Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Disoproxil Fumarate
• Emtricitabine
• Emtricitabine; Rilpivirine; Tenofovir alafenamide
• Emtricitabine; Rilpivirine; Tenofovir disoproxil fumarate
• Emtricitabine; Tenofovir alafenamide
• Emtricitabine; Tenofovir disoproxil fumarate
• Enalapril, Enalaprilat
• Enalapril; Felodipine
• Enalapril; Hydrochlorothiazide, HCTZ
• Enoxaparin
• Entecavir
• Eplerenone
• Epoprostenol
• Eprosartan
• Eprosartan; Hydrochlorothiazide, HCTZ
• Eptifibatide
• Erdafitinib
• Eribulin
• Erlotinib
• Escitalopram
• Esmolol
• Esomeprazole; Naproxen
• Estramustine
• Ethacrynic Acid
• Ethanol
• Etodolac
• Etravirine
• Famotidine; Ibuprofen
• Fenofibric Acid
• Fenoldopam
• Fenoprofen
• Flavocoxid, Flavocoxid; Citrated Zinc Bisglycinate
• Floxuridine
• Fluconazole
• Fludarabine
• Fludrocortisone
• Flunisolide
• Fluorouracil, 5-FU
• Fluoxetine
• Fluoxetine; Olanzapine
• Flurbiprofen
• Fluticasone
• Fluticasone; Salmeterol
• Fluticasone; Umeclidinium; Vilanterol
• Fluticasone; Vilanterol
• Fluvastatin
• Fluvoxamine
• Fondaparinux
• Formoterol; Mometasone
• Foscarnet
• Fosinopril
• Fosinopril; Hydrochlorothiazide, HCTZ
• Furosemide
• Gadoterate meglumine
• Galantamine
• Gallium Ga 68 Dotatate
• Ganciclovir
• Garlic, Allium sativum
• Gemfibrozil
• Gentamicin
• Ginger, Zingiber officinale
• Ginkgo, Ginkgo biloba
• Glimepiride
• Glimepiride; Pioglitazone
• Glimepiride; Rosiglitazone
• Glipizide
• Glipizide; Metformin
• Glyburide
• Glyburide; Metformin
• Gold
• grapefruit juice
• Guanabenz
• Guanfacine
• Heparin
• Hyaluronidase, Recombinant; Immune Globulin
• Hydralazine
• Hydralazine; Hydrochlorothiazide, HCTZ
• Hydralazine; Isosorbide Dinitrate, ISDN
• Hydrochlorothiazide, HCTZ; Irbesartan
• Hydrochlorothiazide, HCTZ; Lisinopril
• Hydrochlorothiazide, HCTZ; Losartan
• Hydrochlorothiazide, HCTZ; Methyldopa
• Hydrochlorothiazide, HCTZ; Metoprolol
• Hydrochlorothiazide, HCTZ; Moexipril
• Hydrochlorothiazide, HCTZ; Olmesartan
• Hydrochlorothiazide, HCTZ; Propranolol
• Hydrochlorothiazide, HCTZ; Quinapril
• Hydrochlorothiazide, HCTZ; Spironolactone
• Hydrochlorothiazide, HCTZ; Telmisartan
• Hydrochlorothiazide, HCTZ; Triamterene
• Hydrochlorothiazide, HCTZ; Valsartan
• Hydrocodone; Ibuprofen
• Hydrocortisone
• Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
• Ibritumomab Tiuxetan
• Ibuprofen
• Ibuprofen lysine
• Ibuprofen; Oxycodone
• Ibuprofen; Pseudoephedrine
• Idelalisib
• Iloprost
• Imatinib
• Immune Globulin IV, IVIG, IGIV
• Indapamide
• Indomethacin
• Inotersen
• Interferon Alfa-2a
• Interferon Alfa-2b
• Interferon Alfa-2b; Ribavirin
• Iodipamide Meglumine
• Iohexol
• Ionic Contrast Media
• Iopamidol
• Iopromide
• Ioversol
• Ioxaglate Meglumine; Ioxaglate Sodium
• Irbesartan
• Isavuconazonium
• Isosulfan Blue
• Itraconazole
• Ivacaftor
• Ixabepilone
• Kanamycin
• Ketoconazole
• Ketoprofen
• Ketorolac
• Labetalol
• Lamivudine; Tenofovir Disoproxil Fumarate
• Lansoprazole; Naproxen
• Leflunomide
• Lepirudin
• Levobetaxolol
• Levobunolol
• Levomilnacipran
• Lisinopril
• Lithium
• Lomustine, CCNU
• Lopinavir; Ritonavir
• Losartan
• Lumacaftor; Ivacaftor
• Lumacaftor; Ivacaftor
• Macimorelin
• Magnesium Salicylate
• Magnesium Salts
• Magnesium Sulfate; Potassium Sulfate; Sodium Sulfate
• Mannitol
• Mecamylamine
• Mechlorethamine, Nitrogen Mustard
• Meclofenamate Sodium
• Mefenamic Acid
• Melphalan
• Mesalamine, 5-ASA
• Methotrexate
• Methoxsalen
• Methyldopa
• Methylprednisolone
• Methylsulfonylmethane, MSM
• Metoprolol
• Mifepristone
• Milnacipran
• Minoxidil
• Mitomycin
• Mitotane
• Mitoxantrone
• Modafinil
• Moexipril
• Mometasone
• Muromonab-CD3
• Nabumetone
• Nadolol
• Naproxen
• Naproxen; Pseudoephedrine
• Naproxen; Sumatriptan
• Nebivolol
• Nebivolol; Valsartan
• Nelarabine
• Neomycin
• Neostigmine
• Nitroprusside
• Non-Ionic Contrast Media
• Olmesartan
• Omacetaxine
• Ombitasvir; Paritaprevir; Ritonavir
• Oritavancin
• Oxaprozin
• Paclitaxel
• Paroxetine
• Pazopanib
• Pegaspargase
• Penbutolol
• Pentamidine
• Pentosan
• Pentostatin
• Perindopril
• Perindopril; Amlodipine
• Phenoxybenzamine
• Phentermine; Topiramate
• Phentolamine
• Photosensitizing agents (topical)
• Physostigmine
• Pindolol
• Piroxicam
• Platelet Inhibitors
• Pneumococcal Vaccine, Polyvalent
• Polyethylene Glycol; Electrolytes
• Polyethylene Glycol; Electrolytes; Ascorbic Acid
• Polymyxin B
• Polymyxins
• Potassium
• Pralatrexate
• Prasugrel
• Prazosin
• Prednisolone
• Prednisone
• Probenecid
• Procarbazine
• Propranolol
• Pyridostigmine
• Quinapril
• Quinolones
• Ramipril
• Regorafenib
• Reserpine
• Reteplase, r-PA
• Ritonavir
• Rivaroxaban
• Rivastigmine
• Romidepsin
• Rucaparib
• Sacubitril; Valsartan
• Salicylates
• Salsalate
• Selective serotonin reuptake inhibitors
• Sertraline
• Sodium Hyaluronate, Hyaluronic Acid
• Sodium Phosphate Monobasic Monohydrate; Sodium Phosphate Dibasic Anhydrous
• Sodium picosulfate; Magnesium oxide; Anhydrous citric acid
• Sodium Polystyrene Sulfonate
• Sotalol
• Spironolactone
• Streptokinase
• Streptomycin
• Streptozocin
• Sulfamethoxazole; Trimethoprim, SMX-TMP, Cotrimoxazole
• Sulfinpyrazone
• Sulfonylureas
• Sulindac
• Tacrine
• Tacrolimus
• Telavancin
• Telbivudine
• Telmisartan
• Telotristat Ethyl
• Temozolomide
• Tenecteplase
• Teniposide
• Tenofovir Alafenamide
• Tenofovir, PMPA
• Terazosin
• Tezacaftor; Ivacaftor
• Thiazide diuretics
• Thioguanine, 6-TG
• Thrombolytic Agents
• Ticagrelor
• Ticlopidine
• Timolol
• Tinzaparin
• Tirofiban
• Tobramycin
• Tolazamide
• Tolbutamide
• Tolmetin
• Topiramate
• Toremifene
• Torsemide
• Tositumomab
• Trandolapril
• Trandolapril; Verapamil
• Trazodone
• Treprostinil
• Tretinoin, ATRA
• Triamcinolone
• Triamterene
• Urea
• Urokinase
• Valacyclovir
• Valganciclovir
• Valproic Acid, Divalproex Sodium
• Valsartan
• Vancomycin
• Vasodilators
• Venlafaxine
• Verteporfin
• Vigabatrin
• Vilazodone
• Vincristine
• Vincristine Liposomal
• Vorapaxar
• Voriconazole
• Vorinostat
• Vortioxetine
• Warfarin
• Zafirlukast