Mannitol Sorbitol

What is Mannitol Sorbitol

Mannitol and sorbitol are hexitols used together in a sterile, nonpyrogenic, hypotonic aqueous solution for urologic nonelectrolytic and nonhemolytic irrigation during transurethral prostatic resection and other transurethral surgical procedures.

Mannitol sorbitol was originally approved for use by the FDA in February 1980.

Indications

  • transurethral surgery
  • urologic irrigation

For urologic irrigation during transurethral prostatic resection and other transurethral surgery procedures

Side Effects

  1. back pain
  2. blurred vision
  3. chest pain (unspecified)
  4. chills
  5. dehydration
  6. diarrhea
  7. diuresis
  8. edema
  9. hypotension
  10. nausea
  11. polydipsia
  12. pulmonary edema
  13. rhinitis
  14. seizures
  15. sinus tachycardia
  16. urinary retention
  17. urticaria
  18. vertigo
  19. vomiting
  20. xerostomia

Monitoring Parameters

  • laboratory monitoring not necessary

Contraindications

  • anuria
  • breast-feeding
  • cardiac disease
  • dehydration
  • diabetes mellitus
  • electrolyte imbalance
  • hepatic disease
  • hyperglycemia
  • hypernatremia
  • hyponatremia
  • parenteral administration
  • pregnancy
  • pulmonary disease
  • renal failure
  • renal impairment

Interactions

There are no drug interactions associated with Mannitol; Sorbitol products.

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